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comparison endocrinology dm2 medications summary clinical diagnosis glp1 abnormal ankles antipsychotics atlas beaus buprenorphine cholinergic diseases dpp4 drugs feet fingernails
Opioid Use Disorder Medications - Pharmacokinetics Buprenorphine is a partial mu-opioid receptor agonist with low intrinsic activity,
activity, high binding ... leading to prolonged effects ... pharmacological effects ... by blocking the effects ... to block their effects
Third Generation Antipsychotics: Mechanisms and Side Effects (Atypical Anti-Psychotics) Example: Aripiprazole Dopamine D2 Receptor Partial Agonist • Binds
Mechanisms and Side Effects ... • Binds to the ... This repetitive binding ... Antidepressant Effects ... #SideEffects #pharmacology
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
15 g QD • Side Effects ... 8.4 g • Side Effects ... daily • Side Effects ... #medications #pharmacology ... #table #comparison
GLP-1 Receptor Agonists - Pharmacology Summary Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
- Pharmacology ... Ozempic), or daily tablet ... pancreatitis Common Side Effects ... Toxicities: • Gl side effects ... Summary #DM2 #diabetes
DPP-4 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
4 Inhibitors - Pharmacology ... GLP-I receptor agonist ... failure Common Side Effects ... definitively cause/effect ... #Summary #DM2 #diabetes
GLP-1 Agonists Adlyxin (Lixisenatide) Daily Bydureon (Exenatide ER) Weekly Ozempic (Semaglutide) Weekly Trulicity (Dulaglutide) Weekly Victoza (Liraglutide) Daily
to treat Type 2 Diabetes ... to the incretin effect ... Common side effects ... #Pharmacology #Dosing ... #Diabetes #DM2
Sedative-Hypnotic Drugs Benzodiazepines: - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
Dose-dependent depressant effects ... Dose-dependent depressant effects ... with few amnestic effects ... of anxiolytic effects ... #comparison #table
Summary of actions of some Cholinergic Agonists Bethanechol • Used in treatment of urinary retention • Binds
retention • Binds ... CNS and cardiac effects ... • Reverses CNS effects ... #Pharmacology # ... Table #Summary
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist Dosing: 3 mg daily x 30 days, then 7 mg
Dosing: 3 mg ... drug to remain stable ... upset as a side effect ... #semaglutide #Diabetes ... #Pharmacology #
Common Ulcers of the Ankles and Feet Chronic Venous Insuffciency This condition usually appears over the medial
Borders are irregular ... Pain affects quality ... Associated findings ... sensation; seen in diabetic ... Associated signs
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