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endocrinology diabetes glp1 management pathophysiology acromegaly allopurinol antipsychotics challenges cholinergic comparison criticalcare dmd dpp4 duchenne features fluid genetics gout inhibitors
GLP-1 Receptor Agonists - Pharmacology Summary Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
- Pharmacology ... Ozempic), or daily tablet ... pancreatitis Common Side Effects ... Toxicities: • Gl side effects ... Summary #DM2 #diabetes
DPP-4 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
4 Inhibitors - Pharmacology ... Summary Mechanisms ... GLP-I receptor agonist ... failure Common Side Effects ... #Summary #DM2 #
Third Generation Antipsychotics: Mechanisms and Side Effects (Atypical Anti-Psychotics) Example: Aripiprazole Dopamine D2 Receptor Partial Agonist • Binds
Mechanisms and Side Effects ... -receptor agonism ... Antidepressant Effects ... #SideEffects #pharmacology ... #diagnosis #psychiatry
GLP-1 Agonists Adlyxin (Lixisenatide) Daily Bydureon (Exenatide ER) Weekly Ozempic (Semaglutide) Weekly Trulicity (Dulaglutide) Weekly Victoza (Liraglutide) Daily
GLP-1 Agonists ... to the incretin effect ... Common side effects ... #Pharmacology #Dosing ... #Diabetes #DM2
Summary of actions of some Cholinergic Agonists Bethanechol • Used in treatment of urinary retention • Binds
CNS and cardiac effects ... • Reverses CNS effects ... Edrophonium • Used for diagnosis ... #Pharmacology # ... Table #Summary
Duchenne Muscular Dystrophy (DMD) The term "Muscular dystrophy" refers to a group of inherited progressive muscle disorders.
Affects 1 per 3500 ... occurs due to defects ... in the gene coding ... #Diagnosis #Features ... #Signs #Genetics
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
and Management Summary ... Acromegaly: frontal bossing ... Macroadenoma direct effects ... multisystemic anabolic effects ... agonist (Carbergoline
Allopurinol Pharmacology Summary Xanthine oxidase inhibitor blocking the formation of new uric acid Initiate 1-2 days prior to
Allopurinol Pharmacology ... Summary Xanthine ... chemotherapy Dosing ... : 100 mg/m2/dose ... 10mL/min Side effects
Fluid Responsiveness and Fluid Tolerance Testing - OnePager Summary Fluid resuscitation can be beneficial when required or
Testing - OnePager Summary ... Distensibility: IVC size reflects ... end of diastole (reflects ... precede other signs ... Tolerance #testing #diagnosis
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