18 results
diabetes endocrinology comparison medications diagnosis management summary dpp4 glp1 inhibitors pathophysiology treatment acromegaly adenosine allopurinol antifungals antipsychotics binders binding buprenorphine
Opioid Use Disorder Medications - Pharmacokinetics Buprenorphine is a partial mu-opioid receptor agonist with low intrinsic activity,
leading to prolonged effects ... pharmacological effects ... by blocking the effects ... to block their effects ... #Pharmacology #
Third Generation Antipsychotics: Mechanisms and Side Effects (Atypical Anti-Psychotics) Example: Aripiprazole Dopamine D2 Receptor Partial Agonist • Binds
Mechanisms and Side Effects ... Receptor Partial Agonist ... -receptor agonism ... Antidepressant Effects ... #SideEffects #pharmacology
GLP-1 Receptor Agonists - Pharmacology Summary Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
- Pharmacology ... Ozempic), or daily tablet ... pancreatitis Common Side Effects ... Toxicities: • Gl side effects ... Summary #DM2 #diabetes
DPP-4 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
4 Inhibitors - Pharmacology ... GLP-I receptor agonist ... failure Common Side Effects ... definitively cause/effect ... #Summary #DM2 #
GLP-1 Agonists Adlyxin (Lixisenatide) Daily Bydureon (Exenatide ER) Weekly Ozempic (Semaglutide) Weekly Trulicity (Dulaglutide) Weekly Victoza (Liraglutide) Daily
GLP-1 Agonists ... to the incretin effect ... Common side effects ... #Pharmacology #Dosing ... #Diabetes #DM2
Metformin - First Line Treatment for Diabetes Type 2 • Start with initial dose of 500 mg
gastrointestinal (GI) adverse effects ... form and consider using ... Indications #Titration #Pharmacology ... #Diabetes #DM2
Duchenne Muscular Dystrophy (DMD) The term "Muscular dystrophy" refers to a group of inherited progressive muscle disorders.
Muscular Dystrophy (DMD ... Affects 1 per 3500 ... occurs due to defects ... in the gene coding ... Diagnosis #Features #Signs
Sedative-Hypnotic Drugs Benzodiazepines: - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
Dose-dependent depressant effects ... Dose-dependent depressant effects ... with few amnestic effects ... of anxiolytic effects ... #comparison #table
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
15 g QD • Side Effects ... 8.4 g • Side Effects ... daily • Side Effects ... #medications #pharmacology ... #table #comparison
DPP4 Inhibitors - Normal and Renal Dosing Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Normal and Renal Dosing ... titrate up to effects ... only few side effects ... #Pharmacology # ... Management #Diabetes #DM2
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