29 results
Opioid Use Disorder Medications - Pharmacokinetics

Buprenorphine is a partial mu-opioid receptor agonist with low intrinsic activity,
leading to prolonged effects ... pharmacological effects ... by blocking the effects ... to block their effects ... #Pharmacology #
Summary of characteristics of Antianginal Drugs

DRUG CLASS, ADVERSE EFFECTS 
 AND DRUG 
INTERACTIONS 

#Antianginal #Medications #Cardiology
CLASS, ADVERSE EFFECTS ... Medications #Cardiology #Pharmacology ... #Management #Therapy ... #Table #Overview
Clozapine blood monitoring for side effects of agranulocytosis and granulocytopenia

#management #psychiatry #antipsychotics #pharmacology #medications #dosing #clozapine
monitoring for side effects ... granulocytopenia #management ... antipsychotics #pharmacology ... #medications #dosing
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
GLP-1 Receptor Agonists ... - Pharmacology ... Ozempic), or daily tablet ... pancreatitis Common Side Effects ... Toxicities: • Gl side effects
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
4 Inhibitors - Pharmacology ... GLP-I receptor agonist ... failure Common Side Effects ... definitively cause/effect ... DPP4 #Inhibitors #Pharmacology
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
GLP-1 Agonists ... Daily GLP-1 Agonists ... to the incretin effect ... Common side effects ... #Pharmacology #Dosing
Sedative-Hypnotic Drugs
Benzodiazepines:
 - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
Dose-dependent depressant effects ... Dose-dependent depressant effects ... with few amnestic effects ... of anxiolytic effects ... #comparison #table
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
15 g QD • Side Effects ... 8.4 g • Side Effects ... daily • Side Effects ... #medications #pharmacology ... #table #comparison
Pearls for Treatment of Alcohol Use Disorder

First-line pharmacotherapies for moderate to severe AUD include naltrexone and
acamprosate Common side effects ... high risk for using ... well-known side effect ... #UseDisorder #Management ... #Medications #Pharmacology
Summary of actions of some Cholinergic Agonists

Bethanechol 
• Used in treatment of urinary retention 
• Binds
some Cholinergic Agonists ... CNS and cardiac effects ... • Reverses CNS effects ... #Pharmacology # ... Table #Summary