26 results
Opioid Use Disorder Medications - Pharmacokinetics

Buprenorphine is a partial mu-opioid receptor agonist with low intrinsic activity,
leading to prolonged effects ... pharmacological effects ... by blocking the effects ... to block their effects ... #Pharmacology #
Effects of Strokes by Location - Anterior vs Posterior Localization

Anterior Circulation 
 - MCA 
 -
Effects of Strokes ... Territory #Symptoms #Signs ... #Localization #Effects ... Neurology #Diagnosis #Table
Nerve agent exposure is a generalized whole-body exposure. Similar to organophosphates, symptoms and signs result from
, symptoms and signs ... Acetylcholine exerts its effects ... than muscarinic effects ... SignsSymptoms #Table
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
GLP-1 Receptor Agonists ... - Pharmacology ... Ozempic), or daily tablet ... pancreatitis Common Side Effects ... Toxicities: • Gl side effects
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
4 Inhibitors - Pharmacology ... GLP-I receptor agonist ... failure Common Side Effects ... definitively cause/effect ... DPP4 #Inhibitors #Pharmacology
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Mechanisms and Side Effects ... Pathophysiology #Pharmacology ... Psychiatry #Diagnosis #Signs
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
GLP-1 Agonists ... Daily GLP-1 Agonists ... to the incretin effect ... Common side effects ... #Pharmacology #Dosing
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Mechanisms and Side Effects ... Pathophysiology #Pharmacology ... Psychiatry #Diagnosis #Signs
Sedative-Hypnotic Drugs
Benzodiazepines:
 - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
Dose-dependent depressant effects ... Dose-dependent depressant effects ... with few amnestic effects ... of anxiolytic effects ... #comparison #table
Anaplasma Infection - Anaplasma phagocytophilum
Pathophysiology: 
 • Obligate, intracellular bacteria
 • Transmitted via blacklegged tick —
scapularis • Infects ... within morulae Signs ... myalgias, shaking chills