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diabetes medications inhibitors comparison management oral summary agonists dosing table classification combination combo dmii hypoglycemics inpatient mellitus pathophysiology pills receptor
Diabetes Combination Tablets - Estimated A1c Lowering Metformin + DPP4 • Janumet (metformin + sitagliptin) •
Metformin + DPP4 ... Metformin + SGLT2 ... Tablets #Oral #DM2 ... #Pharmacology # ... Pills #Endocrinology
DPP-4 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
- Pharmacology ... normally inactivates GLP ... failure Common Side Effects ... #Summary #DM2 # ... diabetes #endocrinology
Diabetes Medications Summary Table Insulin Lifestyle modifications Metformin Sulfonylureas GLP-1 receptor agonists - ↓ major adverse CV events TZDs DPP-4 inhibitors SGLT2 inhibitors -
Sulfonylureas GLP ... events TZDs DPP ... -4 inhibitors SGLT2 ... comparison #management #endocrinology ... #dm2
Mechanism of Action for Common Diabetes Medications • SGLT2i (Dapagliflozin) • TZD (Pioglitazone) • Biguanides (Metformin)
Medications • SGLT2i ... Meglitinides • GLP ... Receptor Agonists • DPP4i ... #Medications #pharmacology ... pathophysiology #endocrinology
GLP-1 Agonists Adlyxin (Lixisenatide) Daily Bydureon (Exenatide ER) Weekly Ozempic (Semaglutide) Weekly Trulicity (Dulaglutide) Weekly Victoza (Liraglutide) Daily
Common side effects ... very similar to DPP4s ... #Pharmacology #Dosing ... #Diabetes #DM2 ... #Endocrinology
DPP4 Inhibitors - Normal and Renal Dosing Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Increase Incretins (GLP-I ... titrate up to effects ... Renal #Dosing #Pharmacology ... Management #Diabetes #DM2 ... #Endocrinology
Effects on body weight of various classes of type-2 diabetes medications. - Metformin - Weight Loss
Effects on body ... Weight Loss + - SGLT ... Weight Loss ++ - GLP ... Weight Loss +++ - DPP ... weightgain #comparison #pharmacology
SGLT2 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
- Pharmacology ... ) Common Side Effects ... #Inhibitors #Pharmacology ... #Summary #DM2 # ... diabetes #endocrinology
GLP-1 Receptor Agonists - Pharmacology Summary Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
GLP-1 Receptor Agonists ... - Pharmacology ... Receptor #Agonists #Pharmacology ... #Summary #DM2 # ... diabetes #endocrinology
Oral Hypoglycemics in Diabetes Management 1 INSULIN SENSITIZER • TZD -
Prandase) • SGLT ... (Adlyxin) • DPP ... by inhibiting DPP ... Diabetes #Management #pharmacology ... #DM2 #DMII #Classification
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