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management neurology signs algorithm hematology classification disorders erythematosus lupus oncology scleroderma sle vasculitis als amyotrophic ana antibodies antinuclear arteritis autoantibodies
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Systemic Sclerosis ... and Symptoms: ... #SSc #rheumatology ... #diagnosis #signs ... #workup
Systemic Sclerosis (Scleroderma) Limited - CREST: • Calcinosis • Raynaud phenomenon • Esophageal dysmotility • Sclerodactyly •
Systemic Sclerosis ... @AnnKumfer #Systemic ... #Sclerosis #Scleroderma ... #diagnosis #signs ... #symptoms #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
technique used to detect ... context of other symptoms ... sclerosis/scleroderma ... ANA #patterns #rheumatology ... #diagnosis #differential
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features of Systemic ... Restrictive lung defect ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... malignancies, Multiple sclerosis ... autoantibodies #signs ... #symptoms #mimickers ... rheumatology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
central nervous system ... Afferent pupillary defect ... SIGNS/SYMPTOMS ... Diagnosis - Based ... Signs and symptoms
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... organ-specific signs ... or symptoms (eg ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Approach to Headaches - Differential Diagnosis Algorithm Red flags (PHANTOMS): • Pattern change, progressively worse, papilledema •
to Headaches - Differential ... Diagnosis Algorithm ... • Neurological deficits ... pupil (AACG) • Systemic ... symptoms and signs
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... site in lymphatic system ... with lymphatic system ... Classic - Nodular Sclerosis ... pattern of spread, B symptoms
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Cord Disorders - Differential ... Diagnosis Framework ... and signs below ... , Scleroderma, Systemic ... sclerosis - MCTD
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