35 results
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Consider sickle cell disease ... Hemolytic #Anemia #Differential ... Diagnosis #Algorithm #workup ... #hematology #testing
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... organ-specific signs ... or symptoms (eg ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune disease ... and Symptoms: ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #workup
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... • Membrane defects ... Causes: • Liver disease ... , spider/snake bites ... classification #hematology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
(aPL) 30-45% Differential ... autoantibodies #signs ... #symptoms #mimickers ... #differential # ... rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Restrictive lung defect ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... PT, aPTT(liver disease ... pylori test (GI symptoms ... #hematology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
technique used to detect ... ANA ≠ Autoimmune Disease ... context of other symptoms ... ANA #patterns #rheumatology ... #diagnosis #differential
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... less common, only affects ... ongoing ↑ LFTs or symptoms ... of liver disease ... Idiosyncratic #differential
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
meningitis), MCC CNS symptoms ... ) Differential Diagnosis ... Syndrome #diagnosis #management ... #signs #symptoms ... #rheumatology #