35 results
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
Defects Bernard-Soulier ... Syndrome • Defect ... Thrombasthenia • Defect ... #table #differential ... #diagnosis #hematology
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... 1 or Type 3) — differentiate ... with qualitative defects ... #disorders #hematology ... #hemepath #differential
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias - Differential ... Diagnosis Algorithm Signs ... : Membrane defects ... Hemolytic #Anemias #Differential ... Diagnosis #Algorithm #hematology
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Leukocytosis - Differential ... malignancy: • Symptoms ... : B-symptoms, bruising ... anemia, ↑ MCV, ↑/↓ platelets ... Diagnosis #Algorithm #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Bleeding / Bruising - Differential ... - Quantitative Defect ... Sequestration Disordered Platelet ... - Qualitative Defect ... Algorithm #Causes #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Defects/Quantity ... Vasculopathy #Purpura #Differential ... #Diagnosis #hematology ... #rheumatology #
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... bleeding from low platelets ... Anemia #diagnosis #management ... #treatment #hematology
Platelet Disorders - Differential Diagnosis Framework

Qualitative Defects:
 • Adhesion
 • Aggregation
 • Secretion

Quantitative Defects:
 • Production:
Platelet Disorders ... - Differential ... Qualitative Defects ... Quantitative Defects ... #Diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... with or without platelet ... , Other enzyme defects ... Hemolytic #Anemia #Differential ... Algorithm #workup #hematology
Thrombocytopenia - Differential Diagnosis and Management Framework for Low Platelets

#Thrombocytopenia #Differential #Diagnosis #Management #hematology #platelets
Thrombocytopenia - Differential ... Diagnosis and Management ... Framework for Low Platelets ... #Diagnosis #Management ... #hematology #platelets