12 results
Diuretic Electrolyte Excretion Effects 
Diuresis, Na+, K+, Mg2+, Ca2+, Cl-, HCO3-, Uric Acid
 - Thiazide Type
Excretion Effects ... Diuresis, Na+, ... Carbonic Anhydrase Inhibitor ... #effects #pharmacology ... #comparison #table
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
DPP-4 Inhibitors ... - Pharmacology ... failure Common Side Effects ... #Inhibitors #Pharmacology ... #Summary #DM2 #diabetes
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Agents Subclass, Drug ... Mechanism of Action, Effects ... others SGLT2 INHIBITORS ... #Medications #Pharmacology ... #summary #table
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
DPP4 Inhibitors ... titrate up to effects ... only few side effects ... #Dosing #Pharmacology ... #Management #Diabetes
Effects on body weight of various classes of type-2 diabetes medications.
 - Metformin - Weight Loss
Effects on body ... classes of type-2 diabetes ... Weight Loss +++ - DPP ... -4 inhibitors - ... weightgain #comparison #pharmacology
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
class of anti-diabetic ... include side effects ... are similar to diuretics ... Side effects include ... #Pharmacology #
Drugs Interacting with Sulfonylureas

Drugs that may reduce the effects of sulfonylureas, leading to loss of glucose
may reduce the effects ... Corticosteroids • Diuretics ... potentiate the effects ... Monoamine oxidase inhibitors ... #Interactions #Pharmacology
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
- Proton-pump inhibitors ... - Calcineurin inhibitors ... - Uncontrolled diabetes ... - Genetic defects ... Low #Magnesium #Table
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
- Pharmacology ... leading to osmotic diuresis ... ) Common Side Effects ... #Pharmacology # ... Summary #DM2 #diabetes
Medications causing Acute Kidney Injury (AKI)
Prerenal:
 • Dehydration: Diuretics
 • Altered intrarenal autoregulation: ACEIs / ARBs,
• Dehydration: Diuretics ... NSAIDs, calcineurin inhibitors ... anticholinergic effects ... #Medications #Drugs ... #pharmacology #