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diagnosis management differential signs hematology oncology sle erythematosus hemophagocytic hlh lymphohistiocytosis neurology syndrome vasculitis ana anthracycline antibodies antinuclear autoantibodies autoimmune
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Restrictive lung defect ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
technique used to detect ... context of other symptoms ... lupus erythematosus ... : Lupus (SLE), Systemic ... ANA #patterns #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... sclerosis, Still's disease ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Motor and sensory deficits ... autoimmune disorders (Systemic ... lupus erythematosus ... diagnosis #neurology #symptoms ... #signs
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... • Treatment: ... months to years) Systemic ... Evolution: Chronic disease ... comparison #table #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
vasculitis) - Affects ... lupus erythematosus ... Symptoms (Sx) in ... purpura: strong sign ... differential #diagnosis #rheumatology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... central nervous system ... Afferent pupillary defect ... SIGNS/SYMPTOMS ... Signs and symptoms
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Symptoms (SX) in ... purpura: Strong sign ... claudication, pulse deficits ... • Progressive symptoms ... Differential #Diagnosis #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome Systemic ... meningitis), MCC CNS symptoms ... Arthritis, AS Treatment ... diagnosis #management #signs ... #symptoms #rheumatology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
disease. ... Episcleritis Signs ... and Symptoms: ... ’s syndrome - Lupus ... Treatment: - Systemic
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