16 results
Clinical Manifestations of Systemic Lupus Erythematosus (SLE)

#Systemic #Lupus #Erythematosus #SLE #Manifestations #Signs #Symptoms #Rheumatology #Diagnosis
Erythematosus (SLE ... ) #Systemic #Lupus ... Erythematosus #SLE ... Manifestations #Signs ... #Symptoms #Rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... Restrictive lung defect ... Thrombocytopenia #Lupus #SLE ... #signs #symptoms ... #diagnosis #rheumatology
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... 40 days ([HCQI reflects ... 200ng/mL Best indications ... #rheumatology # ... pharmacology #levels
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms
Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
Systemic Lupus Erythematosus ... (SLE) - Typical ... Signs/Symptoms ... #Signs #Symptoms ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... #Systemic #Lupus ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
technique used to detect ... context of other symptoms ... erythematosus (SLE ... erythematosus (SLE ... ANA #patterns #rheumatology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
weakness, less systemic ... symptoms, and less ... , holster sign, ... Can also see mechanics ... Myositis #diagnosis #rheumatology
Glaucoma - Emergency Department Management
- All patients should get emergency ophthalmologic consultation
- Start with eye drops
with eye drops (see ... below) and add systemic ... medications if ... or refractory symptoms ... is < 40 mmHg #Pharmacology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Non-autoimmune rheumatologic ... Induced Lupus: • Symptoms ... activation and/or medications ... Erythematosus #Diagnosis #Rheumatology
Sedative-Hypnotic Drugs
Benzodiazepines:
 - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
central nervous system ... or withdrawal symptoms ... of anxiolytic effects ... Hypnotic #Drugs #medications ... #pharmacology #