27 results
Mechanism of Action for Common Diabetes Medications

 • SGLT2i (Dapagliflozin)
 • TZD (Pioglitazone)
 • Biguanides (Metformin)
GLP-1 Receptor Agonists ... #Medications #pharmacology ... pathophysiology #endocrinology
Opioid Use Disorder Medications - Pharmacokinetics

Buprenorphine is a partial mu-opioid receptor agonist with low intrinsic activity,
mu-opioid receptor agonist ... displacing full agonists ... As a partial agonist ... margin of safety in pharmacology ... Comparison #Table #Pharmacology
Third Generation Antipsychotics: Mechanisms and Side Effects
(Atypical Anti-Psychotics) Example: Aripiprazole
Dopamine D2 Receptor Partial Agonist
 • Binds
Mechanisms and Side Effects ... Receptor Partial Agonist ... to D2-receptor agonism ... Antidepressant Effects ... #SideEffects #pharmacology
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
GLP-1 Receptor Agonists ... - Pharmacology ... GLP1 #Receptor #Agonists ... #Pharmacology # ... DM2 #diabetes #endocrinology
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
GLP-1 Agonists ... Daily GLP-1 Agonists ... Common side effects ... #Pharmacology #Dosing ... Diabetes #DM2 #Endocrinology
Clinical Effects of Large and Small Pituitary Tumours
Local complications - Headache, Visual field defect, Disconnection hyperprolactinaemia,
Clinical Effects ... , Visual field defect ... Pituitary #Tumors #Signs ... Symptoms #Diagnosis #Endocrinology
Exogenous Testosterone Side Effects
 • Mood disorder, Depression, Aggression
 • ↑ Erythropoiesis
 • Hypogonadism +/-BPH, prostate
Testosterone Side Effects ... adverse #diagnosis #signs ... symptoms #steroids #endocrinology
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
4 Inhibitors - Pharmacology ... GLP-I receptor agonist ... failure Common Side Effects ... DPP4 #Inhibitors #Pharmacology ... DM2 #diabetes #endocrinology
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
Sulfonylureas - Pharmacology ... CKD Common Side Effects ... Sulfonylureas #Pharmacology ... DM2 #diabetes #endocrinology
Approach to Thyroid Function Tests in the Evaluation of Hyperthyroidism
 • Low TSH, Low normal T4
, and dopamine agonists ... Hyperthyroidism → Signs ... algorithm #diagnosis #endocrinology