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management signs symptoms diabetes dm2 sideeffects adrenal differential medications pathophysiology renal summary dpp4 drugs hepatology insufficiency primary psychiatry sglt2 acidosis
SGLT2 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
- Pharmacology ... ) Common Side Effects ... Toxicities: • AKI ... #Pharmacology # ... DM2 #diabetes #endocrinology
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects • Serotonin Syndrome: - Autonomic Hyperactivity:
Serotonin Reuptake Inhibitors ... Mechanisms and Side Effects ... Pathophysiology #Pharmacology ... SideEffects #Psychiatry #Diagnosis ... #Signs #Symptoms
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting Serotonin Syndrome - Potentially Life
Serotonin-Norepinephrine Reuptake Inhibitors ... Mechanisms and Side Effects ... Pathophysiology #Pharmacology ... SideEffects #Psychiatry #Diagnosis ... #Signs #Symptoms
Medications causing Acute Kidney Injury (AKI) Prerenal: • Dehydration: Diuretics • Altered intrarenal autoregulation: ACEIs / ARBs,
Kidney Injury (AKI ... NSAIDs, calcineurin inhibitors ... anticholinergic effects ... Medications #Drugs #pharmacology ... #differential #diagnosis
DPP-4 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
DPP-4 Inhibitors ... - Pharmacology ... failure Common Side Effects ... #Pharmacology # ... DM2 #diabetes #endocrinology
Distal Renal Tubular Acidosis Distal RTA is the true Nephrogenic RTA and can be truly divided into
• H secretion defect ... ATPase - AEI ... topiramate, CA inhibitors ... • H gradient defect ... Acidosis #RTA #diagnosis
DPP4 Inhibitors - Normal and Renal Dosing Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
DPP4 Inhibitors ... titrate up to effects ... only few side effects ... Renal #Dosing #Pharmacology ... Diabetes #DM2 #Endocrinology
SGLT2 Inhibitors SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
SGLT2 Inhibitors ... SGLT2 inhibitors ... Side effects include ... #Pharmacology # ... DM2 #Diabetes #Endocrinology
Exogenous Testosterone Side Effects • Mood disorder, Depression, Aggression • ↑ Erythropoiesis • Hypogonadism +/-BPH, prostate
Testosterone Side Effects ... SideEffects #adverse #diagnosis ... #signs #symptoms ... #steroids #endocrinology
Clinical Effects of Large and Small Pituitary Tumours Local complications - Headache, Visual field defect, Disconnection hyperprolactinaemia,
Clinical Effects ... , Visual field defect ... Pituitary #Tumors #Signs ... #Symptoms #Diagnosis ... #Endocrinology
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