21 results
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias - Differential ... Diagnosis Algorithm Signs ... : Membrane defects ... Hemolytic #Anemias #Differential ... Diagnosis #Algorithm #hematology
Diagram of different types of bone tumors that can occur around the knee on XRay -
different types of bone ... occur around the knee ... blade of grass sign ... @docskalski #Knee ... #Differential #Radiology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... long bones ... • Differentiate ... BrighamChiefs #Bone ... diagnosis #causes #hematology
Diagram of different types of bone tumors that can occur around the knee on XRay
Age <
occur around the knee ... blade of grass sign ... @docskalski #Knee ... Lesions #Bony #Differential ... #Diagnosis #Radiology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
elbows/wrists and knees ... skin thickening Signs ... (interstitial lung ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
effusion, Restrictive lung ... defect (rare) Raynaud's ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
approximately how long ... Hypogonadism • Bone ... Intrinsic RBC defects ... Production #Index #hematology ... #anemia #differential
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Myositis 4% - Lung ... (aPL) 30-45% Differential ... autoantibodies #signs ... symptoms #mimickers #differential ... #rheumatology
Pleural effusion is not always visible as a meniscus in the costophrenic angle. 
A subpulmonic effusion
the only way to detect ... bubble and the lung ... a patient with signs ... #Clinical #Radiology ... #CXR #CHF #Pleural
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
heliotrope, shawl sign ... discontinued Inclusion Body ... Inflammatory #Myopathies #differential ... diagnosis #comparison #rheumatology