27 results
Cutaneous and Systemic Findings in Dermatomyositis
Cutaneous Findings:
 - Heliotrope sign and edema
 - Nail-fold changes
 -
Cutaneous and Systemic ... - Interstitial lung ... disease - Gastrointestinal ... tract - Cardiac disease ... Dermatomyositis #Diagnosis #Rheumatology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
elbows/wrists and knees ... skin thickening Signs ... (interstitial lung ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
effusion, Restrictive lung ... defect (rare) Raynaud's ... pain (20%) Renal disease ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Myositis 4% - Lung ... (aPL) 30-45% Differential ... autoantibodies #signs ... #rheumatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
rendering the immune system ... Physical Exam/Signs ... cells can indicate disease ... Scoring system: ... workup #oncology #hematology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Pain in Sickle Cell ... Disease Vaso-occlusive ... long bones ... #differential # ... diagnosis #causes #hematology
Diagram of different types of bone tumors that can occur around the knee on XRay -
occur around the knee ... Healed NOF • Giant cell ... blade of grass sign ... Diagnosis #Bony #Differential ... #Radiology #XRay
Diagram of different types of bone tumors that can occur around the knee on XRay
Age <
occur around the knee ... Healed NOF • Giant cell ... blade of grass sign ... Lesions #Bony #Differential ... #Diagnosis #Radiology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
• Interstitial lung ... • Shrinking lung ... Neurologic system ... #joint #pain #differential ... #diagnosis #rheumatology
Ascites - Diagnostic Approach and Differential Diagnosis
The most common causes: cirrhosis, malignancy and heart failure. Approx
shifting dullness detect ... dullness, puddle sign ... incisional). 3) Signs ... of underlying disease ... Routine tests: Cell