10 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
with coagulation defects ... child * Severe cases ... Severe coagulation defects ... AFLP #obstetrics #hematology ... #diagnosis #table
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
with coagulation defects ... . 1) HELLP (Hemolysis ... child * Severe cases ... Obstetrics #OBGyn #Hematology ... Diagnosis #Comparison #Table
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Anemia Intrinsic Causes ... • Membrane defects ... TTP, HUS, DIC, HELLP ... #classification ... #hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Differential Diagnosis Algorithm ... • Wilson's • Pregnancy ... - AFLP, HELLP ... Others #LFTs #Hepatology ... #Causes
Von Willebrand Disease Classification
Type 1 (Accounts for ~3/4 of cases):
 • Defect: Quantitative defect (i.e. not
Willebrand Disease Classification ... for ~3/4 of cases ... Accounts for <5% of cases ... VonWillebrand #Disease #Classification ... #hematology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... biliary obstruction, HELLP ... Toxic: Medication, Pregnancy ... #Acute #algorithm ... #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Fatty Liver of Pregnancy ... Pathophysiology: • Defect ... = nonspecific (nausea ... Preeclampsia, HELLP ... #hepatology #obstetrics
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... • Cryocrit - Detect ... #classification ... #rheumatology #
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... Vascular Causes ... melanoma, myeloma • Pregnancy ... : HELLP • Iatrogenic ... #hepatology
6/02/2022 UPDATE: This assay is designed to detect non-variola orthopoxviruses, including monkeypox virus. It is not
2022-lab-advisory-CLARIFICATION-CDC_Publishes_Non-variola_Orthopoxvirus_PCR_Testing_Procedure ... should use this algorithm ... smallpox-diagnostic-algorithm-poster ... The type of specimen ... See table below