14 results
Opioid Use Disorder Medications - Pharmacokinetics

Buprenorphine is a partial mu-opioid receptor agonist with low intrinsic activity,
As a partial agonist ... margin of safety in pharmacology ... the sublingual tablet ... Pharmacokinetics #Comparison #Table ... #Pharmacology #
Diuretic Electrolyte Excretion Effects 
Diuresis, Na+, K+, Mg2+, Ca2+, Cl-, HCO3-, Uric Acid
 - Thiazide Type
Electrolyte Excretion Effects ... Acid - Thiazide Type ... #electrolytes #effects ... #pharmacology # ... comparison #table
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
GLP-1 Receptor Agonists ... - Pharmacology ... Ozempic), or daily tablet ... GLP1 #Receptor #Agonists ... #Pharmacology #
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
GLP-1 Agonists ... Daily GLP-1 Agonists ... medications to treat Type ... Common side effects ... #Pharmacology #Dosing
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
1) Determine type ... Disease, Mechanical Defect ... vasoactive drug pharmacology ... Vasoactive #Drugs #pharmacology ... management #comparison #table
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
mild ↑CO) - Side effects ... shock - Side effects ... be used in all types ... Inotropes #comparison #table ... #pharmacology #
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
4 Inhibitors - Pharmacology ... Januvia) - Once/day tablet ... GLP-I receptor agonist ... failure Common Side Effects ... DPP4 #Inhibitors #Pharmacology
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Diabetes Mellitus Type ... GLP-1 receptor agonist ... basal insulin in Type ... #Medications #pharmacology ... #comparison #table
Sedative-Hypnotic Drugs
Benzodiazepines:
 - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
5-HT-Receptor Agonist ... uncertain: - Partial agonist ... of anxiolytic effects ... #medications #pharmacology ... #comparison #table
Summary of actions of some Cholinergic Agonists

Bethanechol 
• Used in treatment of urinary retention 
• Binds
some Cholinergic Agonists ... • Reverses CNS effects ... #Cholinergic #Agonists ... #Pharmacology # ... Table #Summary