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diagnosis hematology differential algorithm rheumatology treatment clinical physicalexam anemia oncology ophthalmology alopecia fishing hairloss mfs mucus neurology secondary blood diffuse
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... • Folate Deficiency ... Non-lmmune: • HELLP Syndrome ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... specifically: iron deficiency ... Myelodysplastic syndrome ... Differential #Diagnosis #Causes ... #hematology #secondary
Recurrent / Breakthrough DVT During Anticoagulation Subtherapeutic Anticoagulation Hypercoagulable State - Antithrombin deficiency - Hypercoagulability ot
- Antithrombin deficiency ... Structural - Pelvic masses ... - May-Thurner syndrome ... anticoagulation #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Microcytic" • Iron deficiency ... , Folate deficiency ... Myelodysplastic syndrome ... differential #diagnosis #causes ... #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Kasabach-Merritt syndrome ... necrosis) • VIT K deficiency ... Gardner-Diamond syndrome ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... • Dietary Deficiency ... Myelodysplastic Syndromes ... B12 and Folate Deficiency ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... G6PD deficiency) ... Extravascular #Causes
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
• Loose anagen syndrome ... • Zinc deficiency ... • Copper deficiency ... HairLoss #Alopecia #dermatology ... Diagnosis #Algorithm #causes
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... Diagnosis and Management ... old, ~10,000 new cases ... Myelodysplastic #Syndrome ... #treatment #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Protein S deficiency ... - Protein C deficiency ... • Nephrotic Syndrome ... coagulation and other causes ... pathophysiology #hematology
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