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management oncology differential disease myelodysplastic syndrome thrombocytosis activation adult aplastic arteritis cancer celiac dili disorders druginduced eosinophil eosinophilia essential et
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... effect following treatment ... Iron deficiency anemia ... #Algorithm #Causes ... #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... #Algorithm #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... cytopenias (usually anemia ... only curative treatment ... Myelodysplastic #Syndrome #MDS ... #treatment #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... glucocorticoid treatment ... symptoms (eg, skin ... #Differential #diagnosis ... #hematology #eosinophilia
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
Iron-deficiency anemia ... unresponsive to treatment ... without discernable cause ... Matthew Ho, MD ... #Algorithm #gastroenterology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Headaches • Pale skin ... and petechiae Causes ... Treatment: ... #oncology #hematology ... #diagnosis #management
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
maculopapular skin ... mL Gf consider MAS ... Treatment - Mild ... Stills #disease #AOSD ... #diagnosis #rheumatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Algorithm DILI ... toxic aetiology: Skin ... treatments Search ... for alternative causes ... #Algorithm #hepatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... just beneath the skin ... Out Secondary Causes ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus [SLE], AOSD ... with leukopenia, anemia ... Treatment: • Corticosteroids ... #Management #Hematology ... #Rheumatology
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