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diagnosis differential causes hyponatremia acute injury kidney management gitelman htn hypertension hypotonic low pathophysiology physiologic rhabdomyolysis secondary table treatment workup
Acute Kidney Injury (AKI) - Differential Diagnosis Framework Pre-Renal: • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Kidney Injury (AKI ... : • Hypovolemia ... Abdominal Compartment Syndrome ... Differential #Diagnosis #nephrology ... #causes #algorithm
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... Sodium loss (diuretics ... Present (Uosm ≥100): Hypovolemia ... Cirrhosis, Nephrotic syndrome ... #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Syndrome of Inappropriate ... Malignancy True hypovolemia ... GI losses • Renal ... • Reduced GFR, AKI ... #Hyponatremia #Nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Syndrome of Inappropriate ... Malignancy True hypovolemia ... GI losses • Renal ... • Reduced GFR, AKI ... #Hyponatremia #Nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Workup Algorithm ... investigations depending on clinical ... syndrome: troponin ... #Workup #Algorithm ... Differential #Diagnosis #nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... tubule (DCT) Clinical ... , Renal tubular ... #diagnosis #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Compartment syndrome ... Dermatomyositis Clinical ... declines > ALT) • AKI ... + myoglobin AKI ... causes #treatment #nephrology
Secondary Causes of Hypertension - Differential Diagnosis Algorithm Hypertension - BP > 140/90 (>130/80 for DM) Hypertensive urgency
Differential Diagnosis Algorithm ... based on repeat clinic ... multi-drug resistance) Renal ... • AKI/CKD Mineralocorticoid ... HTN #Secondary #Nephrology
Hyponatremia - Differential Algorithm Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP Hypotonic Hyponatremia: • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
Hyponatremia: • Hypovolemia ... Cirrhosis, Nephrotic Syndrome ... , Chronic Renal ... diagnosis #causes #nephrology ... #sodium #low
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