11 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Kasabach-Merritt syndrome ... - APLS • Acute ... fever • Drug reactions ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Causes of Pseudocellulitis - Differential Diagnosis Framework for Cellulitis Mimics

Cellulitis: Deep skin and subcutaneous fat infection

Pseudo
avoid allergic reactions ... Angioedema • Sweet syndrome ... • Gout • Acute ... • Compartment syndrome ... #dermatology #skin
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
- Transfusion Reactions ... blood donor • Pathophysiology ... without other cause ... At least 3 of (Acute ... #hematology #diagnosis
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Drug Reaction with ... Edema in 70% of cases ... • SJS/TEN • Acute ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... - ACS, AKI, acute ... : • Pathophysiology ... diagnosis #management #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Acute Hemolytic ... , DIC, hypoTN, renal ... Causes purpura & ... Transfusion Related Acute ... diagnosis #management #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Renal Failure ... Differentiation #Syndrome ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... , DIC, hypoTN, renal ... Causes purpura & ... Transfusion Related Acute ... diagnosis #management #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
malignancy (Especially acute ... protein C and S Pathophysiology ... Bleeding (64%) • Renal ... Treat primary cause ... treatment #management #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
changes (POEMS syndrome ... cancers, HCC, renal ... gastric tumors • Hematology ... inflammation (acute ... differential #diagnosis #hematology