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diagnosis management differential renal rheumatology aflp apml coagulation crisis dermatology dic differentiation disseminated diuresis diuretics encephalopathy excretion fatty gap globulin
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Kasabach-Merritt syndrome ... - APLS • Acute ... Decreased Support Of Dermal ... Gardner-Diamond syndrome ... Differential #Diagnosis #hematology
Hepatorenal Syndrome (HRS) - Diagnostic Criteria HRS-AKI (Acute: previously known as HRS Type 1) • ↑ Creatinine
Hepatorenal Syndrome ... Criteria HRS-AKI (Acute ... haematuria, Normal renal ... HRS-NAKI (Non-Acute ... HRSAKI #HRSNAKI #hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... Pregnancy (AFLP) Pathophysiology ... : • Defect in fetal ... = nonspecific (nausea ... Liver #Pregnancy #hepatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... - ACS, AKI, acute ... : • Pathophysiology ... diagnosis #management #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Renal Failure ... Differentiation #Syndrome ... diagnosis #management #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Etiology: • Pathophysiology ... Neurological symptoms: Acute ... , ADEM, Acute toxic ... the underlying cause ... with AEDs until cause
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Torsemide) • Acute ... Kidney stones caused ... hyperaldosteronism • Acute ... Excretion #Diuresis #Nephrology ... #Pharmacology #
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
malignancy (Especially acute ... protein C and S Pathophysiology ... Bleeding (64%) • Renal ... Treat primary cause ... treatment #management #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
changes (POEMS syndrome ... cancers, HCC, renal ... gastric tumors • Hematology ... inflammation (acute ... differential #diagnosis #hematology
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
Crisis: 1) Acute ... anemia (MAHA) Pathophysiology ... • Refractory cases ... #Crisis #rheumatology ... #nephrology #diagnosis
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