16 results
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Hydroxychloroquine ... 200ng/mL Best indications ... Special cases (e.g. renal ... Measurement #SLE #rheumatology ... #pharmacology #
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
severe disease & renal ... block • Sjogren syndrome ... polymyositis overlap syndrome ... Mild disease- Hydroxychloroquine ... Summary #diagnosis #rheumatology
Hydroxychloroquine - Risks and Benefits in Lupus
Benefits:
↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
Hydroxychloroquine ... recommended with other medications ... Lupusreference #Hydroxychloroquine ... Benefits #Lupus #pharmacology ... #sideeffects #rheumatology
Pharmacologic Treatment of Hypertensive Emergencies in Pregnancy
Drug - Dose range - Onset/oeak/duration - Side effects
 -
Pharmacologic Treatment ... , hypotension, fetal ... hypotension, lupus-like syndrome ... Obstetrics #OBGyn #HTN #Pharmacology ... #Medications
Pharmacological Treatment of Hepatorenal Syndrome (HRS)

Midodrine - Alpha agonist incr blood pressure incr renal perfusion pressure
of Hepatorenal Syndrome ... pressure incr renal ... #HepatoRenal #Syndrome ... Nephrology #Management #Pharmacology ... #Medications #Treatment
Causes of Hypomagnesemia
Redistribution:
 - IV glucose
 - Correction of diabetic ketoacidosis
 - IV hyperalimentation
 - Refeeding
metastasis (hungry bone syndrome ... (steatorrhea) Renal ... disorders: - Syndrome ... #differential #medications ... #drugs #pharmacology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
capillary leak syndrome ... • Schnitzler syndrome ... Cryoglobulinemia Renal-centered ... Differential #Diagnosis #hematology ... #oncology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
dL the ULN R - Renal ... plasmacytoma, POEMs syndrome ... MGUS #diagnosis #hematology ... #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... - Antithyroid medications ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome ... and nephrotic syndrome ... and nephrotic syndrome ... Diuresis #Nephrology #Pharmacology ... #Medications #Table