27 results
Pharmacologic Treatment of Hypertensive Emergencies in Pregnancy
Drug - Dose range - Onset/oeak/duration - Side effects
 -
Pharmacologic Treatment ... , hypotension, lupus-like ... syndrome - Nifedipine ... Obstetrics #OBGyn #HTN #Pharmacology ... #Medications
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
200ng/mL Best indications ... Special cases (e.g. renal ... Measurement #SLE #rheumatology ... #pharmacology # ... levels #lupus #management
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... severe disease & renal ... block • Sjogren syndrome ... #Systemic #Lupus ... Summary #diagnosis #rheumatology
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
angiitis of the central ... Churg-Strauss syndrome ... - systemic lupus ... - Sjögren syndrome ... Vessels #Diagnosis #Rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
antiphospholipid syndrome ... S - Systemic Lupus ... Erythematosus (total 50, renal ... #differential #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... APLA/LAC: • Renal ... Vasculitis: • Distal ... activation and/or medications ... Erythematosus #Diagnosis #Rheumatology
Pharmacological Treatment of Hepatorenal Syndrome (HRS)

Midodrine - Alpha agonist incr blood pressure incr renal perfusion pressure
of Hepatorenal Syndrome ... pressure incr renal ... #HepatoRenal #Syndrome ... Nephrology #Management #Pharmacology ... #Medications #Treatment
Hydroxychloroquine - Risks and Benefits in Lupus
Benefits:
↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
and Benefits in Lupus ... recommended with other medications ... Risks #Benefits #Lupus ... #pharmacology # ... #sideeffects #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Features of Systemic Lupus ... Demyelinating syndromes ... Abdominal pain (20%) Renal ... Thrombocytopenia #Lupus ... symptoms #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... disease • Systemic lupus ... lymphadenopathy • Central ... SJIA], systemic lupus ... #Rheumatology