35 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
severe disease & renal ... block • Sjogren syndrome ... polymyositis overlap syndrome ... Summary #diagnosis #rheumatology ... #management
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... Special cases (e.g. renal ... #rheumatology # ... pharmacology #levels ... #lupus #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
(Clinical Dx). ... Behcet disease) Differential ... Oral aphthae : SLE ... #diagnosis #management ... signs #symptoms #rheumatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Splenomegaly - CTD (SLE ... Kasabach-Merritt syndrome ... Associated - SLE ... #rheumatology #
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue - Differential ... Metabolic • Renal ... Arthritis • SLE ... Myasthenia Gravis Pharmacologic ... Chronic Fatigue Syndrome
Hematuria in Post-Renal Transplant Patient
Prevalence up to 12% in the postrenal transplant patient
 • Bacterial: Escherichia
Hematuria in Post-Renal ... (Goodpasture's syndrome ... , SLE, IgA nephropathy ... #Transplant #differential ... #blood #urine #management
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Systemic Lupus (SLE ... Demyelinating syndromes ... Abdominal pain (20%) Renal ... symptoms #diagnosis #rheumatology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... Diagnosis and Management ... iniury, Compartment syndrome ... levels > 8mg/dL See ... #Diagnosis #Management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Fever is the main clinical ... erythematosus [SLE ... #Diagnosis #Management ... #Hematology #Rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... ) Clinical Manifestations ... Demyelinating Syndrome ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management