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Hyponatremia Algorithm - ADH Dependent vs Independent
#Diagnosis #Nephro #Hyponatremia #ADHIndependent #Differential #Algorithm
Algorithm - ADH Dependent ... vs Independent
Hypercalcemia Workup and Differential Diagnosis Framework
1) Determine whether PTH-dependent
2) Assess for other hormonal causes
3) Assess for
Hypercalcemia Workup ... Determine whether PTH-dependent ... Hypercalcemia #Workup
Hypercortisolism (Cushing syndrome) - Simplified Differential Diagnosis Algorithm
Exogenous (ACTH-independent)
Endogenous
 • ACTH-dependent:
    - ACTH-secreting
Exogenous (ACTH-independent ... Endogenous • ACTH-dependent ... the body • ACTH-independent
Hyponatremia Diagnosis Algorithm
UOsm ≥ POsm - Vasopressin-Dependent
 • UNa < 20 mEq/L - Appropriate (↓ EABV)
- Vasopressin-Dependent ... - Vasopressin-independent
Hyponatremia - Differential Diagnosis Algorithm
ADH Independent:
 • Tea and Toast Syndrome, Beer Potomania - Low solute
Algorithm ADH Independent ... ADH Dependent:
Aortitis - Diagnosis and Workup
Clinical History:
 - Fever, weight loss, deterioration of general health
 - Aortic
Diagnosis and Workup ... ) - Symptoms depending ... Aortitis #Diagnosis #Workup
Hypocalcemia - Diagnosis and Management
PTH Independent (↑ PTH)
 • LOW VIT D
    -
Management PTH Independent ... Denosumab PTH Dependent
Causes of Hypercalcemia
Parathyroid hormone–dependent
Primary hyperparathyroidism
Familial hypocalciuric hypercalcemia
Lithium-associated
Tertiary hyperparathyroidism
Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
Parathyroid hormone–dependent ... Parathyroid hormone–independent ... hormone–related protein dependent
Benign Adrenal Mass - Differential Diagnosis Algorithm
Hyperplasia - Often Bilateral
 • Congenital Adrenal Hyperplasia
 • ACTH
Hyperplasia • ACTH Dependent ... • ACTH Independent
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm
ACTH-Dependent (Secondary):
 • Pituitary Dysfunction
 • Hypothalamic Dysfunction
ACTH-Independent (Primary):
Algorithm ACTH-Dependent ... Dysfunction ACTH-Independent