17 results
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
purpura/hemolytic ... , Hematology 2012 ... #Diagnosis #Differential ... #Algorithm #Thrombocytopenia ... #Evaluation
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Count - Differential ... → Refer to hematology ... blood loss, Acute hemolysis ... , Vasculitides, ... #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
DIC/TTP/HUS - Hemolytic ... Pigmented Purpuric Dermatosis ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Thrombocytopenia - Differential Diagnosis Algorithm

Decreased production:
 • Bone marrow suppression
 • Bone marrow failure
 • Bone
Thrombocytopenia ... - Differential ... Diagnosis Algorithm ... #Differential # ... #hematology #platelets
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... with or without platelet ... Schistocytes, thrombocytopenia ... cardiac valve, vasculitis ... #workup #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Diagnosis Algorithm ... Thrombocytopenia ... Sequestration Disordered Platelet ... • Steroids • Vasculitis ... #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential ... Diagnosis Algorithm ... HUS • DIC • Vasculitis ... #Causes #Hematology
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
Diagnosis Algorithm ... < 1800/uL, • platelet ... ↑ Destruction (hemolysis ... #Diagnosis #Algorithm ... #hematology #workup
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... - Bone marrow evaluation ... or if a primary hematologic ... #Differential # ... Causes #Workup #hematology
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
Purpuric Rashes- THE ALGORITHMIC ... with devastating differential ... ; however, an algorithmic ... require emergent evaluation ... #Diagnosis #Dermatology