10 results
Causes of Culture Negative Abscess - Differential Diagnosis Framework
Consider prior antibiotics as a cause of a
Causes of Culture ... antibiotics as a cause ... of a negative culture ... Autoimmune: Crohn's disease ... Differential #Diagnosis #InfectiousDiseases
Endocarditis Algorithm - Infective vs Noninfective Causes
Noninfective:
 • Malignancy
 • Autoimmune disease
 • Systemic infection
Native Valve
Endocarditis Algorithm ... vs Noninfective Causes ... • Autoimmune disease ... • Systemic infection ... • HACEK • Culture-negative
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... antimicrobials, clinical ... but important causes ... (Aspergillus, Candida ... Diseases Fellows
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
Coccidioides - Negative ... Mucorales, Blastomyces dermatidis ... infection (IFI) ... cut-offs defined in clinical ... colonization vs invasive disease
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
are caused by members ... HIV/AIDS, CGD) Clinical ... Diseases Fellows ... Management #treatment #fungal ... #infectiousdiseases
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
Negative: • Bartonella ... Tropheryma Whipplei • Aspergillus ... Septic emboli cause ... Treat underlying cause ... Diagnosis #cardiology #infectiousdiseases
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
polymicrobial infection ... Lung Abscess - Clinical ... • Sputum/Blood cultures ... Prevotella • Fungal ... Blastomyces - Dermatitidis
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
neurological lesion: Clinical ... Infections: - ... Coccidioides, Aspergillus ... Sarcoidosis, Behcet disease ... differential #algorithm
Majocchi’s Granuloma due to Trichophyton rubrum 
This is GMS stain and culture of a skin biopsy
tissues - mainly caused ... Non-dermatophytes: Aspergillus ... Fungal infection ... recommended Mayo Clinic ... Infectious Diseases
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
has five major clinical ... extrapulmonary disease ... stain of clinical ... ASPERGILLOSIS • Aspergillus ... ) #Mycoses #InfectiousDiseases