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differential classification dermatology druginduced hematology nephrology acute aki ana anca antibodies antibody antineutrophil antinuclear aortitis comparison dil diseases erythematosus glomerulonephritis
Lupus Nephritis Primer Class I - Minimal Mesangial Class II - Mesangial Proliferative Class Ill - Focal Proliferative Class IV
Lupus Nephritis ... #Nephritis #SLE ... Classification #Classes ... #differential #diagnosis ... #management #nephrology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Post-strep GN, Lupus ... Nephritis, Cryoglobulinemia ... #differential #diagnosis ... #algorithm #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... nephritis, NPSLE ... Positive in 60-80% of cases ... Erythematosus #Diagnosis ... #rheumatology
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions - Inflammatory
- Differential Diagnosis ... Algorithm Vesicles ... Bullous systemic lupus ... Vesiculobullous #SkinRash ... #Algorithm #causes
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
erythematosus (SLE ... (SPA) • Other Causes ... common bacterial causes ... Mycobacterial Causes ... #rheumatology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... Algorithm Acute ... Malignancy Rapidly Progressive ... Acute Interstitial Nephritis ... #Algorithm #Causes
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Autoimmune • ITP • SLE ... HUS • DIC • Vasculitis ... #Algorithm #Causes ... #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
disorders, or other causes ... Coagulation disorders CAUSES ... Quantity: • Primary Causes ... • Secondary Causes ... Gardner-Diamond syndrome CAUSES
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
cases, drug-dependent ... nephritis, NPSLE ... Positive in 60-80% of cases ... #table #rheumatology ... #diagnosis #management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
proteinuria, rapidly progressing ... tract, and often causes ... such as systemic lupus ... , and SLE) • Urinalysis ... #rheumatology #
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