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diagnosis systemic ana antinuclear differential activation antinxp2 antinxp2dm cerebritis classification cns comparison dermatology dermatomyositis diseases druginduced hematology macrophage mas neurology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Autoantibodies and ... their Disease Associations ... #Associations # ... #table #rheumatology ... #antibodies
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... is clinically suspected ... overlap syndromes ... #erythematosus ... #table #ANA
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in ... Lupus (SLE): ANA ... others (RNP, aPL antibodies ... diagnosis #associations ... #table
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... Syndrome (SS), Polymyositis ... : Lupus (SLE), Systemic ... Arthritis, Sjögren Syndrome ... ANA #patterns #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
SLE) Clinical ... Demyelinating Syndrome ... Cerebrovascular Disease ... the formation of autoantibodies ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Suspect: Clinical ... • Anti-Ro/SSA autoantibodies ... Non-autoimmune rheumatologic ... Clinical Features
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... months) and of autoantibodies ... Erythematosus ( ... : Chronic disease ... #table #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... erythematosus ... SLE], AOSD) • Infection ... #Diagnosis #Management ... #Hematology #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
such as systemic lupus ... erythematosus, ... C-ANCA) pattern: antibodies ... vasculitis, and SLE ... differential #diagnosis #rheumatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
without these autoantibodies ... • Antibodies targeting ... had more severe disease ... • Myoglobin Association ... #rheumatology #
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