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differential rheumatology neurology algorithm classification syndrome vasculitis clinical dermatology management video anisocoria biopsy cerebritis champs cns complement cord cryoglobulins disorders
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... • They can cause ... Cryoglobulins Cause ... Labs/Diagnosis: ... lupus erythematosus
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions - Inflammatory
- Differential Diagnosis ... • Bullous systemic ... lupus erythematous ... Vesiculobullous #SkinRash ... #Algorithm #causes
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Mnemonic C - Cryoglobulinemia ... glomerulonephritis (>90%) S - Systemic ... Lupus Erythematosus ... CHAMPS #Mnemonic #diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... (SLE) Clinical ... autoantibodies that will cause ... permeability Diagnosis ... #SLE #CNS #neurology
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE) SLE patient develops
Lupus Nephritis ... - Diagnostic approach ... associated with systemic ... #Nephritis #diagnosis ... #nephrology #biopsy
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... ANCA +MPO) • Cryoglobulinemic ... inflammation Others: • Lupus ... lupus erythematosus ... vasculitis, and SLE
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
febrile neutrophilic dermatosis ... Causes: - Idiopathic ... such as certain types ... ’s syndrome - Lupus ... Sweet #Syndrome #diagnosis
Horner's Syndrome on Physical Exam A 75yoF was referred in for facial swelling and eyelid changes 1
consistent with a diagnosis ... sympathetic nervous system ... experience, the cause ... ophthalmology #physicalexam ... #neurology #Anisocoria
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 Focal Hand Neuromyotonia Focal neuromyotonia in SLE. A 42 year old with a 10 year
neuromyotonia in SLE ... year history of Systemic ... lupus erythematosus ... was diagnosed. ... #physicalexam
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 Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Hypocomplementemia • Can cause ... TYPE IV RTA, TYPE ... I RTA Diagnosis ... Vasculitis: • 7%, Cryoglobulinemia
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