18 results
Renal Involvement in Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
Renal Involvement ... in Systemic Lupus ... #diseases #SLE ... Erythematosus #venn #nephrology ... #nephritis #classification
Lupus Nephritis Classification Algorithm

#Lupus #Nephritis #Classification #Algorithm #diagnosis #differential #types #rheumatology #nephrology #renal
Lupus Nephritis ... #Lupus #Nephritis ... #Classification ... #rheumatology #nephrology ... #renal
Lupus Nephritis Primer
Class I - Minimal Mesangial
Class II - Mesangial Proliferative
Class Ill - Focal Proliferative
Class IV
Lupus Nephritis ... DrFlashHeart #Lupus ... #Nephritis #SLE ... #Classification ... diagnosis #management #nephrology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic Lupus ... hemolysis • Renal ... #EULARACR #Classification ... #Criteria #SLE
Renal Tubular Acidosis (RTA) 
Type 1 - Failure of secretion
Type 2 - Bicarbonate wasting
Type 4 -
Renal Tubular Acidosis ... proximal features and high ... salt diet #Renal ... Acidosis #RTA #types #classification ... #nephrology #diagnosis
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... severe disease & renal ... • Specific for SLE ... Severe disease- high ... #Systemic #Lupus
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
in 10 to 40% of SLE ... or 0.5 g/day → renal ... severity (ISN/RPS classification ... by 12 months Classification ... #rheumatology #nephrology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Erythematosus (SLE ... Induction Rx: high-dose ... Erythematosus #SLE ... #CNS #neurology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... complements and a high ... Skin Disease Classification ... APLA/LAC: • Renal ... : Drug induced SLE
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... (Pulmonary and renal ... Complex: Systemic lupus ... infiltrates) → high ... differential #diagnosis #nephrology