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diagnosis hematology differential skin neutrophilic apml chronic cll criteria cutaneous differentiation febrile lesions leukemia lymphocytic management manifestations monoclonal myelodysplastic paraproteinemias
Sweet’s Syndrome - Acute febrile neutrophilic dermatosis The syndrome involves fever, painful rash, neutrophilic leukocytosis, and
- Acute febrile ... neutrophilic dermatosis ... #Sweets #Syndrome ... #neutrophilic #dermatosis ... #Skin #Clinical
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome ... neutrophilic dermatosis ... (Sweets Syndrome ... Allergic contact dermatitis ... #dermatology #oncology
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis) Major criteria 1. Abrupt onset of tender
Syndrome (Acute ... Febrile Neutrophilic Dermatosis ... #Syndrome #Acute ... #Neutrophilic #Dermatosis ... #Dermatology
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
myelodysplastic syndrome ... appearing during the disease ... Neutrophilic dermatosis ... differential #diagnosis #dermatology ... #oncology #clinical
Pustular Skin Lesions - Differential Diagnosis Framework What are pustules? • Pustules < 5-10 mm + pus • Material
Erosive pustular dermatosis ... Subcorneal pustular dermatosis ... Acute generalized ... Sweet syndrome ... Differential #Diagnosis #Dermatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... • Neutrophilic dermatosis ... to cold IgG • Lupus ... Subcorneal pustular dermatosis ... Differential #Diagnosis #Oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... febrile neutrophilic dermatosis ... Renal Failure Treatment ... #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... cells can indicate disease ... microglobulin Treatment ... ’s lymphoma or acute ... diagnosis #workup #oncology
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