10 results
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... appearing during the disease ... Neutrophilic dermatosis ... dermatomyositis, SLE ... #dermatology #oncology
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
Connective tissue disease ... (10%) : SLE +++ ... #signs #lesions ... #diagnosis #clinical ... #manifestations
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... - Diagnosis Manifestations ... , Cutaneous mimickers ... #Systemic #Lupus ... autoantibodies #signs
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Rare (SSA+ for cutaneous ... months to years) Systemic ... Evolution: Chronic disease ... #sle #comparison ... #rheumatology #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
inflammation Others: • Lupus ... aphthous ulcers, cutaneous ... as systemic lupus ... purpura: strong sign ... , and SLE) • Urinalysis
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... • Neutrophilic dermatosis ... gangrenosum • Cutaneous ... to cold IgG • Lupus ... #Differential #Diagnosis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... Differential Diagnosis ... as SLE, atherosclerotic ... purpura: Strong sign ... - interstitial keratitis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome Systemic ... M > F Clinical Manifestations ... ) • Cutaneous Lesions ... Oral aphthae : SLE ... #management #signs
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
disease. ... Most common extra cutaneous ... Episcleritis Signs ... ’s syndrome - Lupus ... #dermatology #oncology
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
Erythema ab igne • A dermatosis ... causes: infections (cutaneous ... of necrotizing vasculitis ... #differential #diagnosis ... #dermatology #compared