12 results
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... Neutrophilic dermatosis ... dermatomyositis, SLE ... differential #diagnosis #dermatology ... #oncology #clinical
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
(10%) : SLE +++ ... #dermatology #semiology ... #signs #lesions ... #diagnosis #clinical ... #manifestations
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... Manifestations: ... gangrenosum • Cutaneous ... to cold IgG • Lupus ... Paraproteinemias #Hematology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... of Systemic Lupus ... Sjögrens (15%) Skin ... #SLE #systemic ... symptoms #diagnosis #rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... • Autoimmune diseases ... Henoch-Schönlein purpura) • Cutaneous ... lupus erythematosus ... classification #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitis - Skin ... lupus erythematosus ... purpura: strong sign ... , and SLE) • Urinalysis ... differential #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... 3rd Decade Skin ... #Systemic #Lupus ... Erythematosus #Diagnosis #Rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
, such as SLE, atherosclerotic ... purpura: Strong sign ... / ANCA + MPO) Cryoglobulinemic ... - interstitial keratitis ... Differential #Diagnosis #Rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
disease. ... Most common extra cutaneous ... Episcleritis Signs ... ’s syndrome - Lupus ... Syndrome #diagnosis #dermatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome Systemic ... Manifestations: ... ) • Cutaneous Lesions ... diagnosis #management #signs ... #symptoms #rheumatology