19 results
Renal Involvement in Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
Lupusreference #Renal #diseases ... #SLE #Systemic ... #venn #nephrology ... classification #types ... #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
disease (hematuria ... IgA nephropathy, lupus ... autoAb against type ... #Differential #Diagnosis ... #Nephrology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Cerebrovascular Disease ... #CNS #neurology ... #rheumatology # ... #management #treatment
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Skin, glomeruli ... : - Kidneys: glomerular ... such as systemic lupus ... , and SLE) • Urinalysis ... #rheumatology #
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... Complex: Systemic lupus ... sclerosis • Anti-Glomerular ... #differential #diagnosis ... #nephrology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... : - 10% SLE or ... Labs/Diagnosis: ... (e.g. systemic lupus ... #rheumatology #
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Management of Lupus ... in 10 to 40% of SLE ... Focal LN (<50% of glomeruli ... #rheumatology # ... nephrology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Differential Diagnosis ... Non-autoimmune rheumatologic ... • Type-I Interferonopathies ... #Rheumatology
Renal involvement in 35% of mixed cryoglobulinemia vasculitis 
Associated with : 
 • Absence of skin
cryoglobulinemia vasculitis ... neuropathy • Type ... min/1.73 m2 at diagnosis ... #Management #Rheumatology ... Cryoglobulinemic #Nephrology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... , such as SLE, atherosclerotic ... affects the skin, neurologic ... • Kidneys: Non-glomerular ... #Rheumatology