8 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... #Lupus #Erythematosus ... #Complications ... #pathophysiology ... #diagnosis
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... ) • Systemic lupus ... erythematosus ... in drug-induced SLE ... #diagnosis #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Lupus Erythematosus ... Cerebrovascular Disease ... , PRES Pathophysiology ... #Lupus #Erythematosus ... #SLE #CNS #neurology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often causes arthritis ... as systemic lupus ... purpura: strong sign ... ) pattern: antibodies ... , and SLE) • Urinalysis
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
pain • Extra-CNS complications ... autoimmune disorders (Systemic ... lupus erythematosus ... Manifestations #diagnosis ... #signs
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... as SLE, atherosclerotic ... purpura: Strong sign ... ischemia • Skin: Erythematous ... often causes arthritis
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... • Bilateral signs ... - Sjogren - Vasculitis ... Antiamphiphysin antibodies ... #management #neurology
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
lupus erythematosus ... (SLE), Sjögren’ ... vasculitis - Infectious ... cell lymphoma Pathophysiology ... #management #rheumatology