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differential neurology rheumatology cardiology management symptoms algorithm classification cord dermatology disorders infectiousdiseases inflammatory manifestations myelitis neuromyelitis nmo oncology spinal spinalcord
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
Inflammatory causes ... lupus erythematosus ... Neuromyelitis optica ... ANCA-associated vasculitides ... #Syndromes #neurology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... Butterfly rash, Vasculitis ... #SLE #systemic ... #erythematosus # ... signs #symptoms
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
pain • Extra-CNS complications ... autoimmune disorders (Systemic ... lupus erythematosus ... Manifestations #diagnosis ... #signs
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... as systemic lupus ... erythematosus, ... purpura: strong sign ... , and SLE) • Urinalysis
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
• Autoimmune (SLE ... Vascular: • Systemic ... Septic Emboli Cause ... • Vasculitis ... destructive lesion • Complications
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... as SLE, atherosclerotic ... purpura: Strong sign ... ischemia • Skin: Erythematous ... tract, and often causes
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
disease. ... Episcleritis Signs ... Causes: - Idiopathic ... Leukocytoclastic vasculitis ... ’s syndrome - Lupus
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
• Autoimmune (SLE ... Vascular: • Systemic ... • Vasculitis ... + ↑Suspicion → TEE ... destructive lesion • Complications
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
• Symptoms and signs ... Neuromyelitis optica ... Sarcoidosis, Behcet disease ... - SLE, Scleroderma ... , Systemic sclerosis
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Bilateral signs ... Evaluate for NMO, SLE ... • Infectious causes ... Disorders: - SLE ... - Sjogren - Vasculitis
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