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Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)
Major criteria 
 1. Abrupt onset of tender
Neutrophilic Dermatosis ... Excellent response to treatment ... Dermatosis #Criteria ... #Diagnosis #Hematology ... #Dermatology
Approach to the Rash in a an oncology patient - MINT-C Mnemonic
M - Malignancy: Leukemia cutis,
Dermatoses: Sweet ... Syndrome, Pyoderma ... Neutropenia-specific dermatoses ... #differential # ... MINTC #Mnemonic #dermatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Acute febrile ... neutrophilic dermatosis ... Neutrophilic dermatoses ... Allergic contact dermatitis ... #diagnosis #dermatology
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
myelodysplastic syndrome ... Neutrophilic dermatosis ... #differential # ... diagnosis #dermatology ... #oncology #clinical
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
dermatosis • Pyoderma ... to cold IgG • Lupus ... Subcorneal pustular dermatosis ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
febrile neutrophilic ... dermatosis Diagnosis ... initiation • Differential ... diagnosis #management #hematology ... #oncology
Pustular Skin Lesions - Differential Diagnosis Framework

What are pustules?
• Pustules < 5-10 mm + pus
• Material
inflammatory cells (neutrophils ... Erosive pustular dermatosis ... Subcorneal pustular dermatosis ... Acute generalized ... #Diagnosis #Dermatology