18 results
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... erythematosus (SLE ... Antinuclear #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
: The ANA patterns ... Patterns and Associated ... , Interstitial Pulmonary ... #patterns #rheumatology ... #diagnosis #differential
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
: - SLE, SSc ... Scl70 (in some cases ... Scl-70 (in some cases ... #differential # ... diagnosis #rheumatology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
the face (many differential ... diagnoses, including ... children (pediatric SLE ... #diagnosis #sle ... erythematosus #rheumatology
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Allopecia - Differential ... Diagnosis Framework ... Disease: Discoid lupus ... Scarring Alopecia: Lupus ... #Diagnosis #dermatology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Aortitis - Differential ... Diagnosis Framework ... (RA), Systemic lupus ... erythematosus (SLE ... #Diagnosis #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... Post-strep GN, Lupus ... With associated pulmonary ... #diagnosis #algorithm ... #rheumatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... Pigmented Purpuric Dermatosis ... #Diagnosis #hematology ... #rheumatology #
Papulosquamous Skin Rash - Differential Diagnosis Algorithm
Erythrematous or violaceous papules & plaques with overlying scale
 •
Diagnosis Algorithm ... Christmas tree pattern ... soles • Discoid Lupus ... Papulosquamous #SkinRash ... #causes
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
: • SLE, SSc, ... : • SjS, SLE, DM ... ARUPConsult @ARUPLabs #ANA ... #differential # ... diagnosis #rheumatology