14 results
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
Primary Sjogren’ ... RA) or systemic lupus ... erythematosus ( ... #Syndrome #Pathophysiology ... #Diagnosis #Signs
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Diagnosis Framework ... erythematosus, ... : Lupus erythematosus ... , Loose anagen syndrome ... Examination: • Signs
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... - Budd Chiari Syndrome ... Complications #pathophysiology ... #signs #symptoms ... #diagnosis
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
) Differential Diagnosis ... Algorithm DIFFUSE ... erythematosus ... • Loose anagen syndrome ... erythematosus
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
- Differential Diagnosis ... Algorithm Vesicles ... Bullous systemic lupus ... erythematous ... Vesiculobullous #SkinRash
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
and permanent alopecia ... Differential Diagnosis ... dermatomyositis, Sjogren ... • Nonscarring alopecia ... #Diagnosis #Rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
loss (50%) Eye: Sjögrens ... Demyelinating syndromes ... SLE #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Papulosquamous Skin Rash - Differential Diagnosis Algorithm
Erythrematous or violaceous papules & plaques with overlying scale
 •
- Differential Diagnosis ... Algorithm Erythrematous ... Auspitz sign, Koebner's ... soles • Discoid Lupus ... Papulosquamous #SkinRash
Inflammatory Joint Pain - Differential Diagnosis Algorithm 
Monoarticular
 • Gout (Podagra, Tophi)
 • Pseudogout
 • Early
- Differential Diagnosis ... Arthritis • Systemic Lupus ... Erythematosus ... • Sjögren's (a.k.a ... Sicca) Syndrome
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
disorders (Systemic lupus ... erythematosus, ... Sjögren syndrome ... Manifestations #diagnosis ... neurology #symptoms #signs