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diagnosis differential hematology management antibody common cvid extravascular hemolysis hypogammaglobulinemia immunodeficiency immunology intravascular mcv normocytic rheumatology treatment variable warm
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... , CKD • Hemolytic ... - Extrinsic: Autoimmune ... Infections Macrocytic ... #MCV #Algorithm
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Hemolytic Anemia ... : macrocytic > normocytic ... 2) LOOK FOR a cause ... → Systematic screening ... #Hemolytic #Anemia
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... Differential Diagnosis Algorithm ... Hypochromic & microcytic ... idiopathic, malignancy, autoimmune ... #causes
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Differential Diagnosis Algorithm ... Polychromatic Macrocytes ... Bleed • Hemolysis ... #Causes #Hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Differential Diagnosis Algorithm ... Cold AIHA • Alloimmune ... anemia • ... #Causes #Hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
: Pneumonia • Autoimmune ... thrombocytopenia and autoimmune ... hemolytic anemia ... ) • Systemic granulomatous ... DDX - Other causes
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