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diagnosis algorithm anemia anticoagulation dvt intravascular vte aplastic apml arterial atlas bleeding bruising coagulation dic differentiation disseminated embolism extension extravascular
Causes of Breakthrough/Extension of Thrombosis and Management Algorithm #Anticoagulation #Breakthrough #Thrombosis #Algorithm #Extension #VTE #DVT #Hematology #Management
Causes of Breakthrough ... and Management ... Extension #VTE #DVT #Hematology ... #Differential # ... Causes
Recurrent / Breakthrough DVT During Anticoagulation Subtherapeutic Anticoagulation Hypercoagulable State - Antithrombin deficiency - Hypercoagulability ot
- Antithrombin deficiency ... Structural - Pelvic masses ... - May-Thurner syndrome ... anticoagulation #hematology ... #differential #
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... - Thrombotic ... G6PD deficiency) ... #differential # ... diagnosis #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Differential ... • Nephrotic Syndrome ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... , Pulmonary emboli ... , Thrombotic idiopathic ... key #diagnosis #differential ... #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... necrosis) • VIT K deficiency ... fever • Drug reactions ... #Diagnosis #hematology ... #nonpalpable #dermatology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential ... neutropenia, Kostmann syndrome ... Chediak-Higashi syndrome ... anemia-rare - Copper deficiency-rare ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... thrombopoietin deficiency ... Treat primary cause ... #treatment #management ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... Imaging: CXR- pulmonary ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... , CTLA4 deficiency ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
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