13 results
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
algorithm for the treatment ... for appropriate dosing ... Cancer #Algorithm #Anticoagulation ... #Management #Hematology ... #Oncology
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
patients on chronic anticoagulation ... clearance (calculated using ... interruption per treatment ... table ... may not require anticoagulation
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
(DOAC interactions ... ) Cancer-treatment ... #Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
bleeding risk during ... DOAC, direct oral ... Cancer #Algorithm #Anticoagulation ... #Management #Hematology ... #Oncology
Recurrent / Breakthrough DVT During Anticoagulation

Subtherapeutic Anticoagulation
Hypercoagulable State 
 - Antithrombin deficiency 
 - Hypercoagulability ot
Breakthrough DVT During ... Anticoagulation ... Subtherapeutic Anticoagulation ... - May-Thurner syndrome ... #hematology #differential
Approach to the Rash in a an oncology patient - MINT-C Mnemonic
M - Malignancy: Leukemia cutis,
the Rash in a an oncology ... Dermatoses: Sweet Syndrome ... Gangrenosum, NEH T - Treatment ... #differential # ... MINTC #Mnemonic #dermatology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
Over-anticoagulation ... #pharmacology #treatment ... #medications #table ... decisionaid #cardiology #hematology ... #warfarin #dosing
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
myelodysplastic syndrome ... synchronous or appearing during ... #differential # ... diagnosis #dermatology ... #oncology #clinical
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... initiation • Differential ... Renal Failure Treatment ... #oncology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... 24-48 h and ANC rising ... stenting - Consider anticoagulation ... → no immediate treatment ... and APL (~25 %) during