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oncology differential management causes hemeonc anemia chronic classification hemophagocytic hlh hodgkins lymphocytic lymphohistiocytosis lymphoma pathophysiology syndrome workup aplastic apml bandemia
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... Headaches, bone pain, fever ... Lymphadenopathy • HSM • Fevers ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... cells can indicate disease ... microglobulin Treatment ... leukemia #CLL ... #oncology #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Algorithm Spurious ... Chronic Myelogenous Leukemia ... disorders • Celiac disease ... effect following treatment ... #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
- Differential Diagnosis ... Algorithm Infectious ... • Lymphoma • Leukemia ... • Sickle Cell ... #Hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Symptomatic anemia Diagnosis ... Consider stem cell ... if neutropenic fever ... to MDS or acute leukemia ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
(CLL) - Summary ... ) B symptoms → fevers ... chemotherapy for low-risk disease ... uw_IMresidency #CLL ... #oncology #hematology
Hepatobiliary Manifestations of Sickle Cell Disease Acute sickle cell hepatic crisis: • Fever, acute onset RUQ pain,
Disease Acute ... crisis: • Fever ... Supportive with treatment ... Hepatobiliary #hepatology ... #differential #diagnosis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
- Pel-Ebstein fever ... involved) • No leukemic ... Differential Diagnosis ... Lymphomas • Other hematologic ... #differential #hematology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
neurology, back pain Haematology ... - Sickle cell disease ... #Limping #NWB #Algorithm ... Pathway #Child #Peds ... #Pediatrics #Diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Algorithm • Sickle ... Consider sickle cell ... bartonella (oroya fever ... #hematology #testing
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