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differential causes oncology arthritis blood cll enlarged erythematosus laboratory leukemia lymphocytic markers mds myelodysplasia myelodysplastic platelets rheumatic sle spleen splenomegaly
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
• Polycythemia ... disorders • Celiac ... disease Tissue ... Iron deficiency anemia ... #Hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
T-cell - CD7, CD3 Chronic ... Pseudo Pelger-Huet, Macrocytic ... anemia - ... bcr-able (-) - Polycythemia ... #hematology #Markers
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Myeloproliferative disorders ... (eg. polycythemia ... Inflammatory • Systemic ... Lupus Erythematosus ... #Hematology
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Diagnostic Algorithm ... - Anemia of chronic ... disease - Vitamin ... #hematology #diagnosis ... #differential #workup
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... hemolysis, deficiency anemia ... • Infections: Chronic ... #Algorithm #hematology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Diagnosis Algorithm ... Better call hematology ... normal/high - Chronic ... #Algorithm #workup ... #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ANCA-associated vasculitis, rheumatoid ... lymphopenia, low PLT • Anemia ... : • Chronic B-cell ... #Diagnosis #Rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... affected joint • Systemic ... lupus erythematosus ... #Disease #Rheumatoid ... #Rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cells can indicate disease ... lymphoproliferative disorders ... • Neutropenia, anemia ... #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
common cytopenia: Macrocytic ... Marrow Failure • Chronic ... Myeloproliferative Disease ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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