8 results
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
(Hemolysis, Elevated ... #HELLP #AFLP #Obstetrics ... #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... of Pregnancy (AFLP ... (Hemolysis, Elevated ... #hematology #diagnosis ... #table #comparison
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
, Thrombocytopenia ... of Pregnancy (AFLP ... #hepatology #obstetrics ... #diagnosis #icp ... #HELLP #AFLP
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... infiltration) Differential ... Preeclampsia, HELLP ... Pregnancy #hepatology ... #obstetrics #obgyn
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... : • Liver disease ... #Diagnosis #causes ... #classification ... #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
hemorrhagic skin lesions ... DIC/TTP/HUS - Hemolytic ... deficiency • Liver ... #Diagnosis #hematology ... #nonpalpable #dermatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Vascular Causes ... melanoma, myeloma • Pregnancy ... : HELLP • Iatrogenic ... #hepatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Intravenous Drug Use • Pregnancy ... Syndrome, Ischemic Liver ... atherosclerotic lesions ... coagulation and other causes ... pathophysiology #hematology