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differential erythematosus vasculitis algorithm ana antibodies antinuclear autoantibodies autoimmune classification cord disorders manifestations mimickers myopathy neuromyelitis nmo optica patterns polychondritis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... Glomerulonephritis Myositis ... #SLE #systemic ... #symptoms #diagnosis ... #rheumatology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
• Transverse myelitis ... positive NMO only): Myositis ... lupus erythematosus ... #neurology #symptoms ... #signs
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... anemia 4% - Myositis ... #Systemic #Lupus ... autoantibodies #signs ... #symptoms #mimickers
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... (SLE), Systemic ... : Lupus (SLE), Systemic ... , Myositis, Mixed ... #diagnosis #differential
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis ... • Bilateral signs ... and/or symptoms ... #diagnosis #management ... #neurology #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... • Transverse Myelitis ... APLA/LAC: • Renal ... : • Symptoms limited ... #Systemic #Lupus
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... skin injury) • Neurologic ... #Syndrome #diagnosis ... #management #signs ... #symptoms #rheumatology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
and signs below ... - Transverse myelitis ... Infections: - ... - Sarcoidosis, Behcet ... disease - SLE
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... as systemic lupus ... Symptoms (Sx) in ... vasculitis, and SLE ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulmonary and renal ... as SLE, atherosclerotic ... purpura: Strong sign ... vasculitis • Behcet ... #Rheumatology
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