34 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... Allogeneic stem cell ... only curative treatment ... #Management #treatment ... #hematology #oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
translocation • Types: Classification ... involvement Differential ... Diagnosis of B-Symptoms ... #differential # ... hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... Diagnosis: • ... microglobulin Treatment ... • Richter’s Syndrome ... workup #oncology #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
- Diagnosis and ... Management • ... #Diagnosis #Management ... #treatment #hematology ... #differential
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... pattern of spread, B symptoms ... Lymphoproliferative #Disorders #Classification ... pathophysiology #Hematology ... #differential #
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Script Signs and symptoms ... Symptomatic anemia Diagnosis ... Consider stem cell ... #management #treatment ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Lymphocytic Leukemia (CLL ... minimal tumor burden Diagnosis ... Leukemia #oncology #hematology ... #hemeonc #diagnosis ... #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... changes, stroke symptoms ... organ damage • Treatment ... #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... • Induce blast cell ... : >3 symptoms, or ... initiation • Differential ... #management #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... malignancies -> CLL ... younger pts) Differential ... significance (MGUS), CLL ... hemolytic #anemia #hematology